Norml

Why we need to rebrand the term "HIGH"

“My patients need that THC; they don’t really get a lot of benefit from CBD-only products,” says Bryan Krumm, a psychiatric nurse practitioner who currently works with about one thousand PTSD patients in New Mexico.

He has seen whole-plant cannabis heal all types of patients throughout 25 years in the psychiatry field. He has seen it relieve struggles with PTSD (including his own), as well as other psychiatric woes such as depression and addiction.

“There’s nothing wrong with that psychoactive effect,” he says. “People opposed to cannabis complain that this is a euphoriant and that it makes you high. But that’s what we do in psychiatry. We try to induce euphoria, to lift people’s moods. We don’t want people to be down and low and depressed.”

The difference between Krumm and a lot of other psychiatrists is this: he refuses to ever prescribe another pharmaceutical.

His only exception is the FDA-approved Marinol, a synthetic version of THC developed in the 1980s. A lot of cannabis physicians and practitioners frown upon Marinol because of negative studies and because whole-plant cannabis seems to be more therapeutic with its additional 100+ cannabinoids and multitude of terpene profiles.

But Krumm prescribes Marinol to certain patients when they travel out-of-state to places where cannabis remains prohibited. And some of his patients, contrary to what the studies tell us, actually prefer it to whole-plant medication.

By talking and listening to so many patients, Krumm has discovered that a lot of the studies out there are inaccurate.

In general, the term “high” is supposed to have good connotations, Krumm says.

“If you do the right thing morally and ethically, you’re said to be taking the high road. When we want to get smarter we pursue higher education. We set out to improve ourselves and lift ourselves, and we try to raise ourselves up out of poverty.”

But, like with so many other things applied to cannabis, the idea of getting high immediately gets a negative connotation, he says. “We need to change our understanding and reclaim that term as something positive – which is what it’s supposed to be.”......

Another expert I talked to, Sebastian Marincolo – a cannabis philosopher and writer who has been researching the herb for 10 years now – likes the difference between high and stoned. “When we say stoned we think of that couch-lock state of mind where you’re sedated, not thinking clearly – and for some people this is the desired effect,” he says.

“But the ‘high’ is something else,” Marincolo continues. “It is more euphoric and energetic – a different state of mind which comes with systematic changes in cognition and perception. And most people underestimate all of this and they don’t understand the full bouquet of changes.”

Where a lot of people view the psychoactive element as the adverse side effect of marijuana, Marincolo has methodically explored and laid out what he calls the bouquet of cognitive effects offered by the plant.

In Marincolo’s new book What Hashish Did To Walter Benjamin, he writes about many of these cognitive effects:

  • Hyper focusing
  • Episodic memory retrieval
  • Pattern recognition
  • Enhanced imagination
  • Increased empathy
  • Associative & lateral thinking
  • Deeper introspection

“It doesn’t really give you a total enhancement of cognition, but there are a bunch of possibilities,” Marincolo says. “No matter what you do, you always have some functions enhanced and some that get worse.”

Read the whole article at GreenFlower Media HERE.

National Alzheimer's Day

Today is National Alzheimer’s Day, a day dedicated to the pursuit of medical research that could one day better the lives of millions of people who are affected by this disease. Here are the top 5 ways Cannabis helps these patients.

1. THC Slows Buildup of Neural Plaques

One of the characterizing pathological markers of Alzheimer’s is the buildup of amyloid plaques, a toxic aggregation of peptides in the neural tissue. This 2008 study published in Molecular Pharmaceutics found that THC slowed this amyloid β-peptide (Aβ) overgrowth, a discovery that was again observed in a 2014 study that appeared in Journal of Alzheimer’s Disease. The earlier authors even found a low dose of THC to be “a considerably more effective inhibitor of AChE-induced Aβ deposition than the approved drugs for Alzheimer's disease treatment, donepezil and tacrine, which reduced Aβ aggregation by only 22% and 7%, respectively, at twice the concentration used in our studies.”

 

2. Cannabis Fights Inflammation

Another contributor to the development of Alzheimer’s is inflammation around these amyloid plaques. A 2006 report published in Neuroscience analyzed the role of the endocannabinoid system (ECS) in Alzheimer’s, as activation of CB1 receptor sites had an anti-inflammatory effect. Other research cited in a 2012 review reiterated its importance; one study found that mice bred without CB1 receptors experienced faster cognitive degeneration. The connection between the ECS and neurodegenerative diseases has yet to be developed in human trials, but the premise of this preliminary research alone is encouraging.

 

3. CBD Could Prevent Cell Death

THC isn’t the only compound cannabis has to offer for Alzheimer’s research; the non-psychoactive cannabidiol – better known as CBD – has also hinted at its benefits in preventing cell death. In 2004, researchers noted CBD’s neuroprotective, anti-oxidative, and anti-apoptotic properties, thus reducing neurotoxicity caused by amyloid buildup. These phenomena were again reviewed in a 2009 report that explored promising avenues in cannabinoid therapy, including that which involves a combination of THC and CBD. Noting the synergistic potential of cannabis constituents like CBD and THC, the researchers concluded with cautious optimism:

“The great therapeutic value of CBD, either given alone or in association with THC, derives from the consideration that it represents a rare, if not unique, compound that is capable of affording neuroprotection by the combination of different types of properties (e.g., anti-glutamatergic effects, anti-inflammatory action, and antioxidant effects) that almost cover all spectra of neurotoxic mechanisms that operate in neurodegenerative disorders (excitotoxicity, inflammatory events, oxidative injury, etc.).”

 

4. Cannabinoids Stimulate Cell Growth

So in addition to cannabis’ antioxidant, anti-inflammatory, and neuroprotective attributes, it would appear that cannabinoids may also play a role in the growth of neural tissue in the hippocampus – the area of the brain associated with memory. This mechanism known as “neurogenesis” was explored and discussed in a 2011 study, as well as in a 2007 report that observed cannabinoids “supporting the brain's intrinsic repair mechanisms.”

 

5. Staving Off Other Alzheimer’s Symptoms

One of the more compelling arguments for medical marijuana is its ability to alleviate other symptoms associated with Alzheimer’s, allowing patients to live happier and more functional lives. From appetite stimulation and weight control to motor functioning and agitation reduction, the improved quality of life that cannabis may offer these patients should be enough to warrant a rescheduling of these versatile cannabinoids.

Looking back at decades of research supporting cannabis’ therapeutic benefits in not only Alzheimer’s, but in cancer, pain, epilepsy, stress disorders, sleep disorders, MS, HIV/AIDS, glaucoma, fibromyalgia, gastrointestinal disorders, arthritis, anorexia, diabetes, spasticity, it’s utterly incomprehensible to see cannabis still ranked as a Schedule 1 substance among the likes of heroin.


Cheers to all of the scientists out there making this research happen despite political obstacles and pitfalls.

The First NORML Meeting in The Gorge!

Oregon NORML is dedicated to promoting positive legal, social, and political change with information and action in support of cannabis (marijuana) and the many adults who use it.

First monthly meeting here in The Gorge will be held in our lobby at: 13 Oak Street, Hood River, Oregon 97031
Please bring a lawn chair, pillow, or mat as there is a limited number of seats.
All are welcome, 21 and up. 
Wheelchair accessible.

Facebook: https://www.facebook.com/events/129117954104158/

Google+: https://plus.google.com/u/2/b/112483251989914603026/events/cl10ism09qo14b8l4tbhb2vj0ps